Best Tires for 1999-2021 Ford E-350 Super Duty

Michelin Defender2
Michelin
Michelin Defender2 235/55R19
$254.99
Michelin Pilot Sport 4 SUV
Michelin
Michelin Pilot Sport 4 SUV 255/40R21XL
$480.99
Falken Ziex CT60 A/S
Falken
Falken Ziex CT60 A/S 255/50R20
$267.14
Toyo Tires Observe GSI-6
Toyo Tires
Toyo Tires Observe GSI-6 255/45R20XL
$242.22
Michelin Pilot Sport 4 SUV
Michelin
Michelin Pilot Sport 4 SUV 255/45R20XL
$445.99
Michelin Latitude Tour HP
Michelin
Michelin Latitude Tour HP 235/55R19
$279.99
Falken Wildpeak AT Trail
Falken
Falken Wildpeak AT Trail 255/50R20
$271.76
Mastercraft Courser HXT
Mastercraft
Mastercraft Courser HXT 245/70R17
$260.42
Falken Azenis FK510
Falken
Falken Azenis FK510 255/45ZR20
$267.00
Nitto NT555 G2
Nitto
Nitto NT555 G2 255/45ZR20
$250.00
General Grabber HT
General
General Grabber HT 235/55R19
$335.77
Hankook Optimo H426
Hankook
Hankook Optimo H426 255/45R20
$278.99
Falken Azenis FK460 A/S
Falken
Falken Azenis FK460 A/S 255/45ZR20XL
$239.00
Toyo Tires Open Country A/T III
Toyo Tires
Toyo Tires Open Country A/T III LT245/65R17
$259.54
Nitto Ridge Grappler
Nitto
Nitto Ridge Grappler 255/55R18
$302.00
Hankook DynaPro HT
Hankook
Hankook DynaPro HT LT245/70R17
$281.99
Nitto Motivo 365
Nitto
Nitto Motivo 365 245/50R20XL
$235.00
Toyo Tires Open Country A/T III
Toyo Tires
Toyo Tires Open Country A/T III 255/50R20
$297.82
Toyo Tires Open Country C/T
Toyo Tires
Toyo Tires Open Country C/T LT245/70R17
$376.56
Gladiator XComp AT
Gladiator
Gladiator XComp AT LT245/75R16
$232.59
Falken Aklimate
Falken
Falken Aklimate 255/45R20
$267.45
BFGoodrich Trail-Terrain T/A
BFGoodrich
BFGoodrich Trail-Terrain T/A 235/60R18
$232.99
Pirelli Scorpion WeatherActive
Pirelli
Pirelli Scorpion WeatherActive 255/50R19
$292.16
Uniroyal Tiger Paw Touring A/S
Uniroyal
Uniroyal Tiger Paw Touring A/S 235/60R18
$211.99
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Finding the right tires for your 1999–2021 Ford E-350 Super Duty starts here. Whether you operate a passenger van, cargo hauler, or converted camper, TFS Wheels offers a carefully selected lineup of premium and value tires engineered for the E-350's demanding load requirements. From durable all-season commercial tires to highway touring options, our hand-picked selection covers the fitments this heavy-duty van platform needs. With a fitment guarantee and free shipping on every order, you can shop with confidence knowing your tires will arrive ready to work. Explore tires from leading brands built to handle the weight ratings and daily mileage that E-350 owners depend on.